Mathematics Department, University of North Carolina at Chapel Hill

Position ID: UNCCH-POSTDOC [#11269]
Position Title: Postdoctoral Research Associate
Position Type: Postdoctoral
Position Location: Chapel Hill, North Carolina 27599-3250, United States [map]
Subject Areas: Math/Biology
Application Deadline: 2018/03/09 (posted 2017/11/07, listed until 2018/03/09)
Position Description:    

The labs of Drs. Alan Jones and Tim Elston are in search of a post doc to work on a project, Systems Biology of G Protein Signaling. Heterotrimeric G proteins serve as a signaling nexus in a myriad of normal and diseased cell states. Many extracellular signals (e.g. hormones, peptides, cytokines, lights) are perceived by 7-transmembrane receptors, often referred to as G protein coupled receptors, that stimulate the activation state of the cytoplasmic G protein complex. Interestingly, the majority of non-animal cells (protists, fungi, plants, amoeba and many others) bind GTP without the need for a GPCR. This recent discovery opens up new opportunities to find novel mechanisms that regulate G protein signaling. This project tightly integrates experimental investigations with mathematical modeling to discover and characterize novel signaling motifs that regulate pathway activity in the glucose sensing system of Arabidopsis. The project is a continuation of a well-established collaboration between the labs of Drs. Alan Jones and Tim Elston (Fu, et al 2014 Cell 156:1084-1095).

PhD in a biology-related field

The ideal applicant will have experience with deterministic and stochastic modeling methods, and a willingness to learn the experimental techniques needed to test their mathematical models.

In addition to applying at the UNC website, applicants should post the following at (1) a curriculum vitae/resume; (2) at least three references. In addition, applicants must apply online at to be considered for this position.

The University of North Carolina at Chapel Hill is an equal opportunity, affirmative action employer and welcomes all to apply regardless of race, color, gender, national origin, age, religion, genetic information, sexual orientation, gender identity or gender expression. We also encourage protected veterans and individuals with disabilities to apply.

Application Materials Required:
Submit the following items online at this website to complete your application:
And anything else requested in the position description.

Further Info:
Department of Biology
312 Coker Hall
CB# 27599-3280

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